Red Yeast Rice
Nature's Sunshine Red Yeast Rice (monascus purpureus) a natural statin. The fermented product of rice (oryza sativa) on which red yeast has been used. It has been used in China for hundreds of years, in rice wine as a food preservative and medicinally. In the Chinese pharmacopeia Ben Cao Gang Mu-Dan Shi Bu Yi, published during the Ming Dynasty, red yeast rice was characterised as for blood circulation. Recent research has shown its consumption (typically 14-55 grams per day) to reduce cholesterol concentrations by 11-32% and triglycerides by 12-19%. Monascus produces a substance (monacolin K or Lovastatin) that inhibits HMG CoA reductase, the rate limiting enzyme in cholesterol synthesis. It also contains phytosterols that reduce cholesterol re-absorption. Our use with red yeast rice has shown good to excellent results in over 70% of people who have used it, with reductions in total cholesterol and an increase in HDL cholesterol. I months supply. 120 Capsules.
It is important that this product be taken with CoQ10.
Although most people typically think of high cholesterol as a problem that affects primarily middle aged men, the surprising fact is that high serum cholesterol is most prevalent among white, non Hispanic women, according to the centers for disease control and prevention in Atlanta.
Conventional treatment for high cholesterol usually involves costly statin drugs, which reduce LDL (lo-density lipoprotein) cholesterol. However statin drugs can cause a variety of side effects including gastro intestinal problems such as abdominal pain, constipation, diarrhea, dyspepsia (indigestion), flatulence and nausea, as well as dizziness, headaches, rash and sleep disturbance.
There have also been reported cases of patients experiencing peripheral neuropathy (injury to the nerves in the arms/legs), cataract progression and a progressively decreased therapeutic response to statins after long term treatment. The most serious, although infrequent, adverse event experienced with statin drugs is hepatoxicity (liver damage).
Furthermore, statin drugs inhibit Co-Q10 production, which can lead to congestive heart failure, high blood pressure and low energy.
Fortunately, natural supplements such as red yeast rice have been shown to not only lower total cholesterol, but also raise HDL cholesterol levels and lower lipoprotein(a) a damaging blood fat similar to LDL cholesterol. Individuals with high plasma levels of lipo-protein(a) have a 10 times greater risk for heart disease than individuals with elevated LDL levels.
Red yeast rice has been used for centuries- some sources report its use as far back as the Tang Dynasty, AD 800 - in Chinese cuisine and as a medicinal food to promote blood circulation. Red yeast rice is naturally produced by fermenting rice with red yeast. (Monascus purpureus). The finished product, red yeast rice, contains important substances known as monacolins, which have the ability to inhibit HMG-CoA reductase - an enzyme responsible for cholesterol synthesis in the liver. HMG-CoA reductase inhibitors help regulate the body's cholesterol production and increase the liver's removal of LDL cholesterol from the blood.
Numerous studies have confirmed that red yeast rice demonstrates a direct inhibitory effect on HMG-CoA reductase activity and cholesterol synthesis. Red yeast rice also contains sterols (beta-sitosterol, campesterol, stigmasterol, sapogenin), isoflavones, monounsaturated fatty acids and trace elements that likely assist in lowering serum cholesterol and triglyceride levels.
In fact, red yeast rice has been shown to significantly decrease total cholesterol levels in hyperlipidemic (elevated blood fats) subjects, and has proved to be a cost-saving cholesterol-lowering medication. A systematic review was conducted involving 4 randomized clinical trials on the lipid-lowering effects of red yeast rice in patients with hyperlipidemia. In all studies, statistically significant reductions (16% to 31%) in total serum cholesterol compared with placebo or control or baseline were confirmed, as well as increases in HDL and decreases in LDL cholesterol levels.
HDL is regarded as the good cholesterol, because it helps clean up excess blood fats. LDL cholesterol is called the bad cholesterol, because it accumulates inside arteries, narrowing them and slowing or blocking blood flow - obstructing blood flow causes tissue death and can trigger heart attacks and stokes. Thus, high LDL levels are associated with a higher risk of heart disease.
It is important to note that low HDL cholesterol levels are actually the most important predictor of heart disease in individuals over 70. When HDL levels drop below 35 mg/dL, the risk for heart disease becomes 2 1/2 times greater. Since as many heart attacks strike people with total cholesterol below 200 mg/dL as those with levels higher than 300 mg/fL, the National Institutes of Health, along with leading researchers, recommend maintaining HDL levels above 35 mg/dL. In fact, HDL levels of 60 mg/dL or more actually help to lower your rick for heart disease - for every 1% increase in HDL cholesterol, an individual's risk for heart attack drops 3-4%.
In one of the reviewed clinical trials, 324 hypercholesterolemic adults (those having abnormally high cholesterol levels) taking red yeast rice (1.2 grams daily) for 8 weeks exhibited an average reduction of 22.7% in total cholesterol levels and 30.9% in LDL cholesterol. Furthermore, triglycerides dropped 34.1%, while serum HDL levels increased 19.9%. Thus, researchers concluded that red yeast rice was a highly effective dietary supplement for correcting elevated serum cholesterol and triglycerides.
Another study, a double-blind, placebo-controlled, randomized 12-week trial conducted at UCLA School of Medicine, evaluated the lipid-lowering effects of red yeast rice separate from the effects of diet alone. A total of 65 hypercholestrolemic adults, who were not being treated with lipid-lowering drugs, were given red yeast rice (2.4 grams daily) or placebo and instructed to maintain a diet of 30% fat, 10% saturated fat, and a maximum of 300mg cholesterol daily. After 8 weeks, total cholesterol concentrations had decreased significantly (18% lower) in the red yeast rice group compared to the placebo group. IN addition, LDL cholesterol levels were 23% lower in the treatment group compared to the placebo group. Total triacylglycerol (triglycerides) were also reduced by 16% in the red yeast rice group.
In a randomized, double-blind, placebo-controlled pilot study involving 12 adults with dsylipidemia - abnormal lipid levels (cholesterol and triglycerides) in the blood - related to human immunodeficiency virus (HIV), characterized by hypercholesterolemia, hypertriacylglycerolemia or both, treatment with red yeast rice (2.4 grams daily) for 8 weeks resulted in statistically significant reductions in total cholesterol (31%) and LDL cholesterol (32%) compared with placebo (8% and 26% respectively). Furthermore, no adverse effects were seen with red yeast rice.
Toxicity evaluations of red yeast rice in animals for as long as 4 months have demonstrated no toxicity. Likewise, human trials have shown no elevations of liver enzymes or renal (kidney) impairment. Side effects in clinical trials with red yeast rice have been limited to headaches and gastrointestinal discomfort such as heartburn, flatulence or stomach ache.
Red yeast rice is not recommended during pregnancy or nursing or for woman planning to become pregnant in the near future. Individuals with or at risk for liver or kidney disease or those currently taking any cholesterol-lowering medications should consult your health care provider before using. Cholesterol levels should be checked regularly.
Since red yeast rice provided HMG-CoA reductase-inhibiting activity, supplementation with CoQ10 is recommended. Furthermore, because cholesterol, particularly LDL cholesterol, acts as a carrier for various antioxidants, increasing antioxidant intake when reducing cholesterol is also considered beneficial.
- Supports normal-range cholesterol levels
- Supports the production of HDL (good) cholesterol in the liver
- Assists the liver and circulatory system to maintain their normal healthy bodily functions
Per 2 capsules: Red Yeast Rice (Monascus purpureus) 1140mg.
Other ingredients: Capsule (gelatin, water), vegetable magnesium stearate, silicon dioxide
Take 2 capsules with a meal two to three times daily
Keep out of reach of children. Do not use if you are pregnant, may become pregnant or are breastfeeding, because using this product may cause birth defects. Consult your healthcare provider before using if you are currently taking cholesterol lowering agents. Cholesterol levels should be checked regularly. For adults 20 years of age or older. People with, or at risk for, liver disease should not use this product. Supplementation with CoQ10 is vital for people taking a product like Red Yeast Rice and also pharmacy statin medication.