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SAM-e (S-Adenosylmethionine) is a naturally occurring amino acid found throughout the body with high concentrations in the adrenal glands, liver and brain. It is required in over 40 biochemical reactions, helping with a variety of functions, including mood regulation, cognitive function, general nerve conditions, liver and heart health.
Most of the body's SAM-e is synthesised in the liver from the amino acid methionine, with the help of folic acid and vitamin B12. SAM-e's primary role is supporting healthy levels of serotonin, an important neurotransmitter in the brain known for supporting mood balance. Scientific studies show SAM-e naturally supports mood balance in as little as 7 to 14 days when taken daily. SAM-e provides a source of sulfur, an important compound used to support healthy cartilage and strong joints and for synthesis of taurine and glutathione, used in liver detoxification processes. Factors such as age, certain health conditions and poor diet can impact the amount of SAM-e found in the body. It also appears to help fight premature aging by regenerating new cells, especially in joint and liver tissue. Nature's Sunshine's SAM-e contains 200mg of pure S-Adenosylmethionine tosylate disulfate in each enteric coated tablet. The enteric coating prevents SAM-e from prematurely breaking down in the bottle and also provides for optimal absorption of SAM-e in the small intestine.


May help support healthy mood, mental clarity and focus
Joint support
Helps to promote cell health
Aids in facilitation of muscle/nerve harmony
Supports liver health

Take 2 tablets daily
Refrigerate after opening.

Per tablet
S-Adenosylmethionine (from S-Adenosyl-L-methionineTosylate Disulfate) 200 mg

If you are taking prescription antidepressants or have bipolar (manic) depression, consult your physician before or during the use of this product. Pregnant or breastfeeding women should consult their health care provider prior to taking this supplement.
As always, if taking medication please consult your health care professional for individual concerns.
Always read the label. Use only as directed. If symptoms persist consult your health care professional.