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Femmenessence® MacaPause® is a clinically researched, organic maca supplement formulated specifically for postmenopausal women.
Rather than introducing hormones into the body, MacaPause® nourishes the endocrine system - supporting the body's own natural hormone production and regulation through a proprietary blend of selected maca phenotypes.
Backed by published, double-blind, placebo-controlled human clinical trials showing statistically significant effects on postmenopausal hormones, symptoms, and key health biomarkers, this is one of the few natural supplements in the menopause category with this level of clinical evidence behind it.
- Clinically proven hormone support - published double-blind, placebo-controlled clinical trials show statistically significant improvements in estradiol (over 200% increase on average within two months) and FSH (average 34% reduction within four months) in postmenopausal women
- Broad symptom relief - 84% of women in clinical studies reported relief from hot flashes, night sweats, sleep disruption, and mood fluctuations within 2 days to 8 weeks, rising to 95% with guidance from the Symphony Medical Team
- Mood, energy, and sleep support - statistically significant improvements in mood, emotional steadiness, energy levels, and sleep quality reported in clinical trials compared to placebo
- Heart and bone health - clinical trials showed statistically significant improvements in HDL and LDL cholesterol, triglycerides, blood pressure, and body weight, alongside positive changes in bone density and Z-scores over four months
- Targets the root cause — not just symptoms - nourishes the HPTAO axis (the body's hormonal communication network) to support the body's own natural hormone production rather than introducing exogenous hormones
- USDA Organic, Vegan, Kosher, 3rd-party tested, and free from gluten, soy, dairy, fillers, additives, and preservatives
Per Serve - Serving Size 2 capsules
Organic Gelatinized Maca (Lepidium peruvianum) - 1gm
Hypocotyl Concentrate
Maca-GO® (phenotype ratio for postmenopausal women)
Total carbohydrates - 1gm
Other Ingredients: Organic pullulan vegan capsule.
Take 2 capsules twice daily (4 capsules total per day) with food and water. For best results, use consistently for a minimum of three months. Benefits may be noticed within days, though individual response times vary.
Consult your healthcare professional before use if you are taking prescription medication, have a known medical condition, or have a history of hormone-sensitive conditions. Not intended for use during pregnancy or breastfeeding. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
Femmenessence® MacaPause® sits in a different category from most menopause supplements. Where the majority of natural menopause products focus on individual botanical ingredients - black cohosh, red clover, sage, and similar herbs - MacaPause® is built around a fundamentally different mechanism. It does not contain plant oestrogens or any exogenous hormones. Instead, it uses a proprietary blend of selected maca phenotypes, known as Maca-GO®, to nourish the hypothalamic-pituitary-thyroid-adrenal-ovarian (HPTAO) axis - the hormonal communication network that governs how the body produces and regulates its own hormones.
This approach has been validated in published, peer-reviewed, double-blind, placebo-controlled human clinical trials, which puts Femmenessence® in rare company among natural menopause supplements. The research, published in the International Journal of Biomedical Science, demonstrates statistically significant changes in key postmenopausal hormones - including a greater than 200% average increase in estradiol and a 34% average reduction in FSH - as well as meaningful improvements in menopausal symptoms as measured by validated tools including the Kupperman Menopausal Index and the Greene Climacteric Scale. One particularly compelling design feature of the research was the crossover element: women who improved on Femmenessence worsened when switched to placebo and improved again when switched back - a compelling demonstration of the product's specific effect.
Beyond hormones and symptoms, the clinical research also captured improvements across a wider range of health markers relevant to postmenopausal women, including cardiovascular markers (HDL, LDL, triglycerides, blood pressure, and body weight), bone density, mood and emotional wellbeing, energy, sleep quality, and the appearance of hair, skin, and nails. This breadth of clinical evidence reflects the systemic nature of the endocrine system - when hormonal communication is better supported, multiple areas of health can benefit simultaneously.
The maca used in Femmenessence® is organically grown at high altitude in the Junín plateau of Peru, harvested from specific phenotypes selected for their hormonal support properties, and processed to preserve bioactive compounds including macamides and macaenes. Each batch is third-party tested. The formula is USDA Organic, Vegan, and Kosher, and contains no fillers, additives, or preservatives.
What is Femmenessence® MacaPause® and how is it different from other maca or menopause supplements?
MacaPause® uses a proprietary maca extract called Maca-GO® - a blend of specific Lepidium peruvianum maca phenotypes selected for their ability to support hormonal balance during postmenopause. Unlike standard maca powders or phytoestrogenic herbs, it contains no plant oestrogens or exogenous hormones. Instead it nourishes the HPTAO axis - the body's hormonal communication network - to support the body's own natural hormone production and regulation.
What clinical evidence supports MacaPause®?
It is one of the few natural menopause supplements backed by published, peer-reviewed, double-blind, placebo-controlled human clinical trials. Studies showed statistically significant improvements in estradiol (over 200% average increase within two months), FSH (34% average reduction within four months), validated menopausal symptom scores, cardiovascular markers, bone density, mood, energy, sleep, and hair, skin, and nail health.
How quickly does it work?
In clinical studies, 84% of postmenopausal women reported symptom relief within 2 days to 8 weeks, with an average improvement time of 21 days. Symphony Natural Health recommends allowing a minimum of one to two months for full assessment. When supported by their Medical Team, real-world success rates rose to 95%.
Is this suitable for women who have experienced surgical menopause?
A published case report describes a woman who entered immediate menopause following hysterectomy and oophorectomy and reported improvements in hot flashes, night sweats, sleep, and mood over eight weeks while using MacaPause® as part of a broader wellness plan. Women who have experienced surgical menopause should consult their healthcare provider before use.
Is MacaPause® organic, hormone-free, and allergen-free?
Yes. MacaPause® contains no synthetic or plant-based hormones. It is USDA Organic, Vegan, Kosher, and third-party tested. Free from gluten, soy, dairy, and common allergens, with no fillers, additives, or preservatives.
How long does one box last and can I take it alongside medication?
Each box contains 120 capsules providing a 30-day supply at four capsules per day. If you are taking hormone replacement therapy, prescription medication, or have a hormone-sensitive medical history, consult your healthcare professional before use.